Anti-KRT5 Polyclonal Antibody (HY310014)

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Datasheet

Overview

Catalog No.

HY310014

Description

Anti-KRT5 Polyclonal Antibody (HY310014) is a rabbit polyclonal antibody detecting KRT5 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Human, Pan troglodytes, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Mouse, Bos taurus, Human, Pan troglodytes, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KRT5 (Thr166-Leu474).

Target

Type-II keratin Kb5, Keratin, type II cytoskeletal 5, K5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, KRT5, Keratin-5

Purification

Purified by antigen affinity column.

Accession

P13647

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Keratin, type II cytoskeletal 5 (KRT5) is a ~62 kDa protein. Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress. Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes.

Note

For research use only.

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