Anti-HPV31 E7/Protein E7 Antibody (SAA2461) (VK556143)

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100ug
1mg

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Datasheet

Overview

Catalog No.

VK556143

Description

Anti-HPV31 E7/Protein E7 Antibody (SAA2461) [SAA2461] (VK556143) is a mouse monoclonal antibody in ELISA, IHC.

Species reactivity

Human papillomavirus type 31 (HPV31)

Applications

ELISA, IHC

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA2461

Expression system

Mammalian Cells

Clonality

Monoclonal

Endotoxin level

<10 EU/mg

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P17387

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternate Names

Protein E7, E7

Background

Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.

Note

For research use only.

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