Anti-Human GPX2 Polyclonal Antibody (HA536014)

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Overview
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Datasheet

Overview

Catalog No.

HA536014

Description

Anti-Human GPX2 Polyclonal Antibody (HA536014) is a rabbit polyclonal antibody detecting GPX2 in WB, IHC, ELISA. Suitable for Human, Mus musculus, Rattus norvegicus, Callithrix jacchus, and Hylobates lar.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Homo sapiens, Mus musculus, Rattus norvegicus, Callithrix jacchus, Hylobates lar, Macaca fuscata fuscata, Pongo pygmaeus, Sapajus apella

Applications

WB, IHC, ELISA

Host species

Rabbit

Isotype

IgG

Species

Homo sapiens (Human)

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GPX2 (Met1-Ile190).

Target

GPX2

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Accession

P18283

RRID

Anti-Human GPX2 Polyclonal Antibody (abinScience Cat# HA536014, RRID:AB_3730144)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Glutathione peroxidase 2, GPx-2, GSHPx-2, EC:1.11.1.9, Gastrointestinal glutathione peroxidase, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI, Glutathione peroxidase-related protein 2, GPRP-2, Phospholipid hydroperoxide glutathione peroxidase GPX2, EC:1.11.1.12, GPX2

Background

Glutathione peroxidase 2 (GPX2) is a ~21 kDa protein. Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide.

1. Schwarz, M. et al. (2023) Redox biology 59, 102593. PMID: 36608588

2. Chu, FF. et al. (1993) The Journal of biological chemistry 268, 2571-6. PMID: 8428933

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human GPX2 polyclonal antibody at 1ug/mL on recombinant Human GPX2 (Catalog No. HA536012).

References

Datasheet

Anti-Human GPX2 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GPX2 Polyclonal Antibody (HA536014)

Overview

Images

References

Datasheet

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