

| Catalog No. | HA067013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-BKbeta4 K+ channel Antibody (L18A/3) [L18A/3] (HA067013) is a mouse monoclonal antibody detecting BKbeta4 in IHC, WB.
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| Applications | IHC, WB | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | L18A/3 | ||||
| Clonality | Monoclonal | ||||
| Target | Calcium-activated potassium channel subunit beta-4, BK channel subunit beta-4, Calcium-activated potassium channel, subfamily M subunit beta-4, KCNMB4, Hbeta4, Slo-beta-4, BKbeta4, Charybdotoxin receptor subunit beta-4, K(VCA)beta-4, Maxi K channel subunit beta-4 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q86W47 | ||||
| RRID | Anti-BKbeta4 K+ channel Antibody (L18A/3) (abinScience Cat# HA067013, RRID:AB_3728520) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Calcium-activated potassium channel subunit beta-4 (KCNMB4) is a ~23 kDa protein. Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-BKbeta4 K+ channel Antibody (L18A/3)
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