

| Catalog No. | VK530014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human metapneumovirus (strain CAN97-83) (HMPV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HMPV SH/Small hydrophobic protein (Asn51-Asp179). | ||||||||
| Target | Small hydrophobic protein, SH | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6WB95 | ||||||||
| RRID | Anti-HMPV SH/Small hydrophobic protein Polyclonal Antibody (abinScience Cat# VK530014, RRID:AB_3723651) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Small hydrophobic protein (SH) is a ~20 kDa protein. Viroporin that forms a ion channel probably displaying low ion selectivity. Plays a role in counteracting host innate immunity by inhibiting TLR7/MyD88/TRAF6 signaling and STAT1 phosphorylation, leading to down-regulation of type-I IFN. 1. Masante, C. et al. (2014) Journal of virology 88, 6423-33. PMID: 24672047 2. Hastings, AK. et al. (2016) Virology 494, 248-56. PMID: 27131212 3. Bao, X. et al. (2018) Viruses 10. PMID: 29789500 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-HMPV SH/Small hydrophobic protein polyclonal antibody at 1ug/mL on recombinant HMPV SH/Small hydrophobic protein (Catalog No. VK530012).
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