Anti-Human CDKN2A/p16INK4a Polyclonal Antibody (HW820014)

Name: Anti-Human CDKN2A/p16INK4a Polyclonal Antibody
Brand: abinScience
SKU: HW820014
Price: 96 USD
Availability: InStock

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20ug
50ug
100ug

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Overview
Images
References
Datasheet

Overview

Catalog No.

HW820014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CDKN2A/p16INK4a (Met1-Asp156).

Target

p16-INK4, Multiple tumor suppressor 1, MTS-1, MTS1, Cyclin-dependent kinase 4 inhibitor A, p16-INK4a, Cyclin-dependent kinase inhibitor 2A, CDKN2A, p16INK4A, CDKN2, CDK4I

Purification

Purified by antigen affinity column.

Accession

P42771

RRID

Anti-Human CDKN2A/p16INK4a Polyclonal Antibody (abinScience Cat# HW820014, RRID:AB_3723220)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cyclin-dependent kinase inhibitor 2A (CDKN2A/p16INK4a) is a ~16 kDa protein. Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human CDKN2A/p16INK4a polyclonal antibody at 1ug/mL on recombinant Human CDKN2A/p16INK4a (Catalog No. HW820012).

References

Datasheet

Anti-Human CDKN2A/p16INK4a Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CDKN2A/p16INK4a Polyclonal Antibody (HW820014)

Overview

Images

References

Datasheet

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