



| Catalog No. | MF815109 |
|---|---|
| Description |
InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse.
Highlights
|
| Species reactivity | Mouse |
| Applications | FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization |
| Host species | Rat |
| Isotype | lgG2b |
| Clone ID | 2.43 |
| Clonality | Monoclonal |
| Target | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2, cd8 |
| Endotoxin level | <1 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01731 |
| RRID | InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) (abinScience Cat# MF815109, RRID:AB_3730135) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. |

SDS-PAGE for InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43)

Detects CD8a/Lyt2 (Catalog No. MF815011) in indirect ELISAs.




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