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Timely TGFβ signalling inhibition induces notochord

10.1038/s41586-024-08332-w

Affiliations
Tiago Rito, Ashley R G Libby, Madeleine Demuth, Marie-Charlotte Domart, Jake Cornwall-Scoones, James Briscoe

DOI: 10.1038/s41586-024-08332-w

Abstract
The formation of the vertebrate body involves the coordinated production of trunk tissues from progenitors located in the posterior of the embryo. Although in vitro models using pluripotent stem cells replicate aspects of this process

Keywords
TGF-β,notochord

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Catalog No. Product Name Description Target
HF977096 TGF-β Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB