TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8+ T cell activation

10.1038/s41467-025-56029-z

Affiliations
Kun Wei, Ruifeng Li, Xiaohong Zhao, Bowen Xie, Tian Xie, Qinli Sun, Yongzhen Chen, Peng Wei, Wei Xu, Xinyi Guo, Zixuan Zhao, Han Feng, Ling Ni, Chen Dong

DOI: 10.1038/s41467-025-56029-z

Abstract
T cell activation is accompanied by extensive changes in epigenome. However, the high-ordered chromatin organization underpinning CD8

Keywords
IL-2，T cell，CD8

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TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8+ T cell activation

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