Unlocking the Potential of Phage Display Technology
Phage display technology has transformed molecular screening by enabling the targeted presentation of foreign proteins on bacteriophages. Among different phage systems, M13 filamentous phage stands out as the preferred vector due to its unique properties.
Understanding Antibody–Antigen Interactions: The Critical Role of Antibody Complex Density
Recent advancements in antibody research underscore the critical role of antigen–antibody complex density in influencing antibody effectiveness. A comprehensive study published in Frontiers in Immunology highlighted that antibodies forming high-density complexes with their targets significantly enhance immune responses, including complement-dependent cytotoxicity (CDC) and antibody-dependent cellular cytotoxicity (ADCC). Using advanced methodologies like hydrogen-deuterium exchange mass spectrometry (HDX-MS) and biolayer interferometry (BLI), the researchers established that antibodies with high-density complex formation exhibited superior pathogenic potential due to enhanced structural stability of antigen–antibody complexes. These findings reinforce the importance of precise antibody selection for phage display workflows and screening, illustrating how high-performance tools such as the Abinscience M13 monoclonal antibody—optimized for detecting low antigen levels and ensuring specific and stable binding—are essential for advancing research accuracy and reliability in biotechnology and therapeutic antibody development.
Optimize Your Phage Display Workflow with Abinscience M13 Monoclonal Antibody
Looking for a high-affinity, high-sensitivity, and highly specific M13 monoclonal antibody for your phage display experiments? Abinscience offers a powerful solution designed to optimize your workflow.
Key Advantages:
- Ultra-high sensitivity: Detects as low as 10⁶-10⁷ pfu/ml.
- Exceptional specificity: Recognizes only M13 phages, ensuring no cross-reactivity.
- Versatile compatibility: Works seamlessly with ELISA, flow cytometry, Western blot (WB), and more.
- Reliable stability: Ensures high batch-to-batch consistency for standardized and reproducible results.
Experimental Data
Fig.1 Analysis of M13 Mouse antibody-HRP sensitivity
Fig.2 Background binding of different tags to M13 antibodies
Top-Selling M13 Antibody Products
| Catalog No |
Product Name |
| VK473025 |
Anti-Bacteriophage M13 Vll/G8P/Capsid Protein G8P Monoclonal Antibody (1A191) |
| VK473915 |
Anti-Bacteriophage M13 Capsid Protein G8P Monoclonal Antibody (1A191), HRP |
| VK473415 |
Anti-Bacteriophage M13 Capsid Protein G8P Monoclonal Antibody (1A191), FITC |
| VK473325 |
Anti-Bacteriophage M13 Capsid Protein G8P Monoclonal Antibody (1A191), Biotin |
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