Unlock the Power of dsRNA Detection with Abinscience’s Anti-dsRNA Antibodies

Unlock groundbreaking insights into double-stranded RNA (dsRNA) detection with Abinscience’s high-quality anti-dsRNA antibodies. As a key indicator of viral infection and a trigger of innate immune responses, dsRNA is central to virology, immunology, and RNA research. Abinscience delivers premium anti-dsRNA solutions—featuring clones J2, K1, and K2—offering unmatched specificity, sensitivity, and reliability to accelerate discoveries in viral replication, mRNA vaccine development, and immunotherapy.

Advanced Anti-dsRNA Antibodies for Cutting-Edge Research

Double-stranded RNA (dsRNA) is a vital target in scientific research, driving viral lifecycle studies and immune signaling pathways. Abinscience offers a curated portfolio of high-performance monoclonal antibodies, meticulously engineered to provide precise dsRNA detection, empowering researchers with tools for virology, RNA-based drug development, and immune mechanism studies.

Fig. 1. Binding Strength of Anti-dsRNA Antibodies (J2, J5, K1, K2) in Detecting Synthetic and Natural dsRNA (Absorbance at A405)

Precision Anti-dsRNA Antibodies

Our anti-dsRNA antibodies are designed for exceptional specificity and sensitivity, making them ideal for advanced research applications:

• Anti-dsRNA Antibody, Clone J2 – The gold standard for dsRNA detection, offering ultra-high sensitivity for dsRNA longer than 30 bp. Perfect for ELISA, dot blot, and immunofluorescence in viral infection studies.
• Anti-dsRNA Antibody, Clone K1 – Excels in detecting diverse synthetic dsRNA fragments (e.g., poly(A)·poly(U)), with peak absorbance of 2.0 at 405 nm after 16 hours, ideal for virology assays.
• Anti-dsRNA Antibody, Clone K2 – Optimized for complex samples, achieving absorbance of 1.820 with natural L-dsRNA (10 ng, 16-hour incubation), the strongest among tested clones for natural dsRNA binding.

Each antibody undergoes rigorous quality control, validated for specificity, sensitivity, and batch consistency, ensuring reliable results for global research efforts.

Powerful dsRNA Research Tools: Driving Scientific Discoveries

dsRNA’s role in viral infections, mRNA vaccine purity, and immune activation makes it a critical target for research. Our anti-dsRNA antibodies accelerate breakthroughs in key areas:

• Virology Research – Detect and localize dsRNA in infected cells (e.g., SARS-CoV, Reovirus) to decode viral replication mechanisms and support antiviral strategies.
• mRNA Vaccine Development – Use J2 and K2 with ELISA kits to ensure dsRNA impurity detection, enhancing vaccine safety and efficacy.
• Immune Pathway Studies – Investigate dsRNA-triggered pathways (RIG-I, MDA5, TLR3) to advance immunotherapy and antiviral research.

dsRNA Detection: Mechanisms and Impact

Fig. 2. Anti-dsRNA Monoclonal Antibodies Precisely Detect and Localize dsRNA in Virus-Infected Cells

dsRNA serves as a hallmark of viral replication and a potent activator of immune receptors like RIG-I, MDA5, and TLR3, triggering interferon production and antiviral responses. Abinscience’s antibodies provide the precision needed to study these processes, from viral infection dynamics to immune signaling amplification.

Anti-dsRNA Research Products:

Why Choose Abinscience for Your dsRNA Research?

Abinscience’s anti-dsRNA antibodies stand out as industry leaders, offering:

• Unmatched Quality – Stringently tested for specificity, sensitivity, and batch-to-batch consistency, ensuring dependable results.
• Superior Precision – Engineered for reproducible outcomes across virology, RNA, and immunology research, trusted by top labs globally.
• Global Trust – Cited in leading publications, our antibodies are the choice of researchers worldwide driving dsRNA-related breakthroughs.

Elevate your dsRNA detection research with Abinscience’s trusted, high-performance antibodies. Our solutions empower you to uncover new insights into virology, mRNA development, and immune responses—faster and with greater confidence.

Discover Abinscience Anti-dsRNA Products Now!

References

[1] Schönborn et al. (1991) Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts. Nucleic Acids Res. 19:2993.
[2] Lukacs (1994) Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA. J. Virol. Methods 47:255.
[3] Lukacs (1997) Detection of sense:antisense duplexes by structure-specific anti-RNA antibodies. In: Antisense Technology. A Practical Approach, C. Lichtenstein and W. Nellen (eds), pp. 281-295. IRL Press, Oxford.
[4] Weber et al. (2006) Double-Stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. Journal of Virology 80 (10):5059.
[5] Knoops et al. (2008) SARS-Coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum. PLOS Biology 6 (9):e226.
[6] Richardson et al. (2010) Use of antisera directed against dsRNA to detect viral infections in formalin-fixed paraffin-embedded tissue. Journal of Clinical Virology 49: 80.