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  • InVivo Plus
    abinScience’s InVivo Plus™ antibodies target CD3, PD-1, CD4, CD8, Ly6G and more, providing low-endotoxin, in vivo-grade solutions for animal model research.
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  • Bacteria & Viruses related products
    abinScience provides high-quality tools for studying viruses, superbugs, and parasites, including monkeypox, Ebola, and other emerging pathogens, supporting diagnostics, vaccine development, and therapeutic discovery.
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  • Neuroscience
    abinScience provides tools for studying Alzheimer's, Parkinson's, and Huntington's disease, supporting biomarkers, diagnostics, and therapy development in neuroscience.
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  • Therapeutic Targets
    abinScience provides tools for studying therapeutic targets, including CD3E, CTLA4, PD1, PDL1, B7-H3, CEA, CD200R1, SIRPA, and CCR8, supporting biomarkers, diagnostics, and therapy development.
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  • DNA/RNA Research Antibodies
    abinScience offers anti-dsRNA antibodies (J2, K1, K2), widely recognized in virology, immunology, and RNA research for their exceptional specificity and sensitivity, empowering scientists to explore the RNA world
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  • Biotoxin Antibodies
    Reliable antibodies for botulinum, ricin, tetanus, and other toxins, enabling sensitive detection and toxin research.
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  • Autoimmune Diseases
    High-specificity antibodies and ELISA kits for key targets like TNF-α, IL-6, IFN-γ, PD-1, and CTLA-4, enabling reliable cytokine detection and immune regulation studies.
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  • MHC Complex
    Specific antibodies for MHC I, MHC II, and related molecules, supporting antigen presentation, immune response, and disease research.
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  • TACAs Antibodies
    Targeting tumor-associated carbohydrate antigens (Tn, STn, MUC1, CA15-3, CA72-4) to support cancer immunotherapy and biomarker research
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  • Model Organism
    Model organisms are vital tools used by researchers around the globe. These organisms share many genes with humans, are easily maintained in the lab, and have short generation times that make it easy to study the effects of genetic manipulations.
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  • West Nile Virus (WNV) Research: Structure, Pathogenesis & Diagnostic Solutions by abinScience
    West Nile Virus (WNV), a neurotropic flavivirus spread by Culex mosquitoes, is explored in this article for its structural biology, pathogenesis, and diagnostic innovations. The ~50 nm virion features a pseudo-icosahedral envelope and a ~11 kb RNA genome, with E protein flexibility aiding immune escape and NS1 enhancing vascular permeability (Nature, 2023; Cell Reports, 2024). Climate change boosts outbreak risks with >200 thermal degree-days (Lancet Planetary Health, 2024). Discover cutting-edge vaccine trials like ChimeriVax-WN02 and mRNA solutions (J Infect Dis, 2024), plus abinScience’s diagnostic tools with 95-98% specificity, perfect for 2025 virology research.
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  • InVivoMAb™ Plus: Precision In Vivo Antibodies for Animal Models by abinScience
    The abinScience InVivoMAb™ Plus series offers over 400 high-quality in vivo antibodies, validated for purity, specificity, and functionality, ideal for research in cancer, autoimmune diseases, and infectious diseases. This page details the activity validation experiments and ELISA tests of anti-PD-1 and anti-PD-L1 antibodies in mouse models (B16-F10 and CT26), demonstrating significant tumor suppression and antigen-binding capabilities. The product list includes a range of antibodies and isotype controls designed for immune regulation and tumor immunotherapy, supported by batch stability and traceability.
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  • CD47: Exercise While Resting! A Potential “Exercise Mimetic Factor” for Precise Muscle Metabolism Activation
    A 2025 Cell Reports Medicine study reveals CD47-blocking antibodies mimic exercise by activating AMPK in skeletal muscle, promoting fat loss, improving glucose tolerance, and preserving muscle mass in mice. Unlike GLP-1 or SGLT2 drugs, CD47 targets muscle specifically, avoiding non-target organ side effects. This “exercise mimetic” shows promise for obesity, diabetes, and muscle degenerative diseases.
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  • Science Discovery: The Role of Erythropoietin (EPO) in Tumor Immune Evasion
    Recent research has uncovered a critical role for erythropoietin (EPO) in tumor immune evasion. Tumor cells secrete EPO, which, through the EPOR signaling pathway, suppresses the immune function of macrophages, aiding tumors in escaping immune surveillance. Blocking the EPO/EPOR signaling enhances the efficacy of PD-1 immunotherapy, offering a novel strategy for cancer treatment.
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  • Salmonella 2025 Outbreak? Be Ready with abinScience Tools
    The 2025 Salmonella Enteritidis outbreak underscores the urgent need to understand its virulence mechanisms and develop effective vaccines. This article highlights key structural features, immune evasion strategies like the PhoPQ system, and current vaccine research, supported by research tools from abinScience.
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  • Unveiling EBV-Induced B Cell Migration: The Critical Roles of FAK and IL-10
    Epstein-Barr Virus (EBV) drives B cell migration to distant organs via CCL4/CCR1 signaling, FAK-mediated transendothelial migration, and IL-10 secretion, promoting lymphoma and autoimmune diseases. FAK inhibitor Defactinib reduces migration and EBV spread in vivo. abinScience offers high-precision EBV proteins and antibodies, supporting virology research with innovative tools for studying these mechanisms.
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  • SLC34A2 (NaPi2b) Antibodies & Recombinant Proteins for Cancer Research | abinScience
    Explore validated SLC34A2 (NaPi2b) antibodies and recombinant proteins from abinScience, supporting cancer pathway studies, biomarker discovery, and targeted therapy development across multiple tumor types.
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  • Can a Single Blood Test Reveal Cancer Risk? New Study Unveils Non-Invasive Screening for HPV-Related Head and Neck Cancer
    A Harvard-led study in Clinical Cancer Research introduces HPV-DeepSeek, a liquid biopsy detecting HPV-related head and neck squamous cell carcinoma (HNSCC) via blood tests. With 98.7% sensitivity and specificity, it outperforms traditional methods, identifying HPV genotypes, mutations, and tumor staging. This non-invasive approach could revolutionize early cancer detection, reducing reliance on invasive biopsies.
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  • COVID-19 Resurgence in 2025: Omicron NB.1.8.1 Drives Surge with Enhanced Immune Escape
    Since April 2025, China has faced a resurgence of COVID-19, with positivity rates in outpatient and inpatient settings rising sharply from 7.5% to 16.2% and 3.3% to 6.3%, respectively. Southern provinces report higher infection rates than the north, with the Omicron NB.1.8.1 variant driving the surge due to its enhanced immune escape capabilities. Symptoms remain mild, including sore throat, low-grade fever, and cough. The pandemic is expected to peak in late May and subside by late June. abinScience offers high-quality SARS-CoV-2-related proteins and antibodies to support cutting-edge virology research.
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  • Cell Unveils Snake Venom Antidote: Snake Handler Bitten 200 Times Over 18 Years Provides Super-Immune Serum
    A groundbreaking study in Cell reveals a new hope for snakebite treatment using broad-spectrum antibodies LNX-D09 and SNX-B03, derived from a snake handler bitten 200 times over 18 years. Targeting long- and short-chain neurotoxins (3FTxs), these antibodies neutralize venom from 19 deadly snakes, offering protection in mice when combined with varespladib. This innovation could revolutionize antivenom therapy, addressing global snakebite challenges, particularly in Africa, Asia, and Latin America.
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  • FGF21 — An Emerging Metabolic Hormone Target for Reversing Metabolic Dysfunction-Associated Steatohepatitis
    A 2025 Cell Metabolism study reveals FGF21’s role in reversing metabolic dysfunction-associated steatohepatitis (MASH) through central nervous system and hepatic mechanisms. By reducing liver triglycerides and cholesterol, FGF21 improves steatosis and fibrosis in mouse models. Long-acting FGF21 drugs like Efruxifermin show promise in phase III trials, positioning FGF21 as a key therapeutic target for metabolic liver diseases.
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  • Ebola Sudan Strain: Key Research Developments, Vaccine Trials, and abinScience Research Reagents
    In early 2025, Uganda faced an Ebola outbreak caused by the Sudan strain, prompting global attention. In response, clinical trials targeting the Sudan strain were launched. The Ebola virus, a member of the Filoviridae family, has several key proteins like GP, NP, and VP40 critical for its replication and infectivity. Additionally, research reagents, including recombinant proteins and antibodies, are crucial for advancing Ebola research, with companies like abinScience supplying essential tools for scientists worldwide.
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