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Recombinant Human CCR8 Protein, N-His-KSI (HW444032)

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор

Каталожный номер	HW444032
Описание	Recombinant Human CCR8 Protein, N-His-KSI (HW444032) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P51685
Длина белка	Met1-Lys35&Lys64-Tyr73&Tyr94-Lys107&Asp130-Thr146&Tyr172-Met202&His223-Arg238&His264-Tyr280&Glu305-Leu355
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	C-C CKR-8, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, CC-CKR-8, CCR-8, CCR8, CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, GPRCY6, TER1
Фон	C-C chemokine receptor type 8 is a ~40 kDa protein. G protein-coupled receptor that can bind a variety of chemokines, such as CCL1, CCL8, CCL16, CCL18. Regulates monocyte and eosinophil chemotaxis. Undergoes internalization upon CCL18 binding, leading to induced migration and calcium flux of highly polarized Th2 cells. In microglial cells, promotes phagocytosis with CCL18 through NF-kappa-B and Src signaling pathways. Stimulation of the CCL1-CCR8 signaling axis protects the gut from acute intestinal damage. 1. Islam, SA. et al. (2013) The Journal of experimental medicine 210, 1889-98. PMID: 23999500 2. Ding, D. et al. (2022) Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 42, 19-28. PMID: 35041514
Примечание	For research use only

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Recombinant Human CCR8 Protein, N-His-KSI.pdf

Formula

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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Recombinant Human CCR8 Protein, N-His-KSI