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Research Grade imzokitug (HW444146)

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Research Grade imzokitug

Research Grade imzokitug

Цена(USD): $

Спецификация:

100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит

Обзор

Каталожный номер	HW444146
Описание	imzokitug (HW444146) is a research-grade recombinant antibody targeting CD198. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Изотип	IgG1, Kappa
Виды	Human
Клоональность	Monoclonal
Цель	CD198/CCR8
Чистота	>95% as determined by SDS-PAGE.
Номер доступа	P51685
Форма	Liquid
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	2919583-43-8
Фон	C-C chemokine receptor type 8 (CD198/CCR8) is a ~40 kDa protein. G protein-coupled receptor that can bind a variety of chemokines, such as CCL1, CCL8, CCL16, CCL18. Regulates monocyte and eosinophil chemotaxis. Undergoes internalization upon CCL18 binding, leading to induced migration and calcium flux of highly polarized Th2 cells. In microglial cells, promotes phagocytosis with CCL18 through NF-kappa-B and Src signaling pathways. Stimulation of the CCL1-CCR8 signaling axis protects the gut from acute intestinal damage. 1. Islam, SA. et al. (2013) The Journal of experimental medicine 210, 1889-98. PMID: 23999500 2. Ding, D. et al. (2022) Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 42, 19-28. PMID: 35041514
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade imzokitug

Ссылки

Даташит

Research Grade imzokitug.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

Рекомендация

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Список дистрибьюторов

Research Grade imzokitug