Research Grade Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1) (VK681016)

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Спецификация:

100ug
1mg

Количество:

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Каталожный номер	VK681016
Описание	Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1) (VK681016) is a research-grade recombinant antibody targeting NS1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Hepatitis C Virus (HCV)
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Изотип	IgG1-kappa
ID клона	MBL-HCV1
Система экспрессии	Mammalian Cells
Клоональность	Monoclonal
Цель	NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
Уровень эндотоксинов	Please contact the lab for this information.
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P27958
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Альтернативные названия	MBL-HCV1, MBLHCV1
Фон	Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

Western blot

Western blot analysis was performed using anti-glycoprotein E2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant hepatitis C virus (Catalog No: VK681011)
Lane 2: negative control
Bioactivity

Detects recombinant HCV NS1/gp68/gp70/Envelope glycoprotein E2 (Catalog No: VK681011) in indirect ELISA