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Research Grade Barzolvolimab (HY163016)

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Research Grade Barzolvolimab

Research Grade Barzolvolimab

Research Grade Barzolvolimab

Research Grade Barzolvolimab

Research Grade Barzolvolimab

Research Grade Barzolvolimab

Цена(USD): $

Спецификация:

100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит

Обзор

Каталожный номер	HY163016
Описание	Barzolvolimab (HY163016) is a research-grade recombinant antibody targeting CD117. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Chimeric
Изотип	IgG1-kappa
Система экспрессии	Mammalian Cells
Клоональность	Monoclonal
Цель	Mast/stem cell growth factor receptor Kit, p145 c-kit, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, KIT, PBT, Piebald trait protein, Proto-oncogene c-Kit, SCFR, CD117
Уровень эндотоксинов	Please contact the lab for this information.
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P10721
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Альтернативные названия	CDX-01592438203-51-9
Фон	Mast/stem cell growth factor receptor Kit (CD117) is a ~109 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SEC-HPLC

SEC-HPLC detection for Research Grade Barzolvolimab.
Bioactivity

Detects CD117/KIT in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Barzolvolimab.

Ссылки

Даташит

Research Grade Barzolvolimab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

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Volume

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g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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V₁ (Stock Vol.)

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Working Solution

C₂ (Working Conc.)

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Список дистрибьюторов

Research Grade Barzolvolimab