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| カタログ番号 | ZA029033 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (11F) [11F] (ZA029033) is a mouse monoclonal antibody detecting Beta-toxin Cl13 in ELISA, Neutralization, SPR.
Highlights
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| 種反応性 | Centruroides limpidus (Mexican scorpion), Centruroides baergi (Scorpion) (Centruroides nigrovariatus baergi) | ||||
| アプリケーション | ELISA, Neutralization, SPR | ||||
| 宿主種 | Mouse | ||||
| アイソタイプ | IgG2a | ||||
| クローンID | 11F | ||||
| クローン性 | Monoclonal | ||||
| ターゲット | Beta-toxin Cl13, CliNaTxBet37, Beta-toxin Cb3, Centruroides limpidus (Mexican scorpion), Centruroides baergi (Scorpion) (Centruroides nigrovariatus baergi) | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | C0HK69, C0HLR5 | ||||
| RRID | Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (11F) (abinScience Cat# ZA029033, RRID:AB_3729012) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Beta-toxin Cl13 (Cb3) is a ~8 kDa protein. Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Inhibits sodium channels Nav1.4/SCN4A, Nav1.5/SCN5A and Nav1.6/SCN8A. Also has a weak inhibitory effect on Nav1.2/SCN2A. Is lethal to mice. 1. Olamendi-Portugal, T. et al. (2017) Peptides 87, 34-40. PMID: 27871874 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Mexican scorpion Beta-toxin Cl13/Cb3 Antibody (11F)
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中国武漢市深敦寺路666号C棟、武漢、430206
