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| カタログ番号 | VK584013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Rabies virus G/Glycoprotein Antibody (17C7) [17C7] (VK584013) is a human monoclonal antibody detecting Glycoprotein in ELISA, Neutralization. Suitable for Rabies virus (RABV).
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| 種反応性 | Rabies virus (RABV) | ||||
| アプリケーション | ELISA, Neutralization | ||||
| 宿主種 | Human | ||||
| アイソタイプ | IgG1, kappa | ||||
| クローンID | 17C7 | ||||
| クローン性 | Monoclonal | ||||
| ターゲット | G, Glycoprotein | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P03524 | ||||
| RRID | Anti-Rabies virus G/Glycoprotein Antibody (17C7) (abinScience Cat# VK584013, RRID:AB_3725279) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||
| 注意事項 | For research use only. |
SEC-HPLC detection for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
SDS-PAGE for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
Detects Recombinant RABV G/Glycoprotein, C-His (Cat No.: VK584011) in indirect ELISA.
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