Anti-Rabies virus G/Glycoprotein Antibody (17C7) (VK584013)

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20ug
50ug
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1mg

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Datasheet

Vista general

Número de catálogo

VK584013

Descripción

Anti-Rabies virus G/Glycoprotein Antibody (17C7) [17C7] (VK584013) is a human monoclonal antibody detecting Glycoprotein in ELISA, Neutralization. Suitable for Rabies virus (RABV).

Reactividad de especies

Rabies virus (RABV)

Aplicaciones

ELISA, Neutralization

Especie huésped

Human

Isotipo

IgG1, kappa

ID de clon

17C7

Clonalidad

Monoclonal

Objetivo

G, Glycoprotein

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P03524

RRID

Anti-Rabies virus G/Glycoprotein Antibody (17C7) (abinScience Cat# VK584013, RRID:AB_3725279)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Nota

For research use only.

Imágenes

Bioactivity

SEC-HPLC detection for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
SDS-PAGE

SDS-PAGE for Anti-Rabies virus G/Glycoprotein Antibody (17C7).
Bioactivity

Detects Recombinant RABV G/Glycoprotein, C-His (Cat No.: VK584011) in indirect ELISA.