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| カタログ番号 | VK431013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (5B3) [5B3] (VK431013) is a mouse monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, FCM, Neutralization.
Highlights
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| 種反応性 | Hendra virus (isolate Horse/Autralia/Hendra/1994) & Nipah virus | ||||
| アプリケーション | ELISA, FCM, Neutralization | ||||
| 宿主種 | Mouse | ||||
| アイソタイプ | IgG1, kappa | ||||
| クローンID | 5B3 | ||||
| クローン性 | Monoclonal | ||||
| ターゲット | F, Fusion glycoprotein F0, Protein F | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O89342, Q9IH63 | ||||
| RRID | Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (5B3) (abinScience Cat# VK431013, RRID:AB_3725238) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 別名 | 5B3, h5B3.1 | ||||
| 背景 | Fusion glycoprotein F0 is a ~59 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (5B3).
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