

| Каталожный номер | VK556014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Реактивность видов | Human papillomavirus type 16 | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Изотип | IgG | ||||||||
| Клоональность | Polyclonal | ||||||||
| Иммуноген | E. coli - derived recombinant HPV16 E7/Protein E7 (His2-Pro98). | ||||||||
| Цель | Protein E7, E7 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P03129 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-HPV16 E7/Protein E7 polyclonal antibody at 1ug/mL on recombinant HPV16 E7/Protein E7 (Catalog No. VK556012).




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