描述 (Description)
Trastuzumab，中文名曲妥珠单抗 ， 是一种人源化 IgG1 单克隆抗体，其以高亲和力与 HER2 选择性结合。Trastuzumab 可用于 HER2 阳性转移性乳腺癌和 HER2 阳性胃癌 的研究。
货号 (Catalog No.)
Abs0169
宿主 (Host species)
Humanized
种属反应性 (Species reactivity)
Human
状态 (Form)
液体
保存溶液 (Storage buffer)
0.01M PBS, pH 7.4.
浓度 (Concentration)
1 mg/ml
纯度 (Purity)
>95%.
克隆类型 (Clonality)
Monoclonal
同种型 (Isotype)
IgG1-kappa
应用 (Applications)
阳性对照抗体/Biosimilar (科研用)
靶标 (Target)
p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein
纯化方式 (Purification)
Protein A/G purified from cell culture supernatant.
内毒素水平 (Endotoxin level)
Please contact with the lab for this information.
表达系统 (Expression system)
Mammalian
Accession
稳定性和存储 (Stability and Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
别名 (Alternative Names)
timigutuzumab, 4D5-8, 4D5V8, Herceptin, rhuMab HER2, CAS: 180288-69-1
