Anti-Human uPAR Monoclonal Antibody (1A451) (HX035055)

Name: Anti-Human uPAR Monoclonal Antibody (1A451)
Brand: abinScience
SKU: HX035055
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HX035055
Description	Anti-Human CD87/PLAUR/uPAR Monoclonal Antibody (1A451) [1A451] (HX035055) is a mouse monoclonal antibody in ELISA, FCM, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2b
Clone ID	1A451
Clonality	Monoclonal
Immunogen	Recombinant Human CD87/PLAUR/uPAR (Leu23-Arg303).
Tested applications	FCM
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q03405
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR
Background	Urokinase plasminogen activator surface receptor (CD87/PLAUR) is a ~36 kDa protein. Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. 1. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461
Note	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human UPAR antibody. HUCCT cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human UPAR antibody monoclonal antibody (Catalog #HX035055, Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog #MF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet