Anti-Human Adiponectin/Acrp30 Monoclonal Antibody (1A404) (HS862045)

Name: Anti-Human Adiponectin/Acrp30 Monoclonal Antibody (1A404)
Brand: abinScience
SKU: HS862045
Price: 194 USD
Availability: InStock

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Overview

Catalog No.	HS862045
Description	Anti-Human Adiponectin/ADPN Monoclonal Antibody (1A404) [1A404] (HS862045) is a mouse monoclonal antibody detecting Adiponectin in CLIA. Suitable for Human.
Species reactivity	Human
Applications	CLIA
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG
Clone ID	1A404
Immunogen	Human Adiponectin/ADPN Protein.
Target	Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Adiponectin (ADPN) is a ~26 kDa protein. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Note	For research use only.