Research Grade Sirukumab (HY328036)

データシート製品共有情報コピー

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100ug
1mg

数量:

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概要
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データシート

概要

カタログ番号	HY328036
説明	Research Grade Sirukumab (HY328036) is a human monoclonal antibody detecting Hybridoma growth factor in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG1-kappa
発現システム	Mammalian Cells
種	Human
クローン性	Monoclonal
ターゲット	Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P05231
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
別名	CNTO 136, 1194585-53-9
背景	Interleukin-6 (Hybridoma growth factor,BSF-2,IFN-beta-2,CDF,IL6,Interleukin-6,IL-6,B-cell stimulatory factor 2,Interferon beta-2,IFNB2,CTL differentiation factor) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
注意事項	For research use only. Not suitable for clinical or therapeutic use.