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Research Grade Rafivirumab (VK632026)

Research Grade Rafivirumab
Research Grade Rafivirumab
Research Grade Rafivirumab
Research Grade Rafivirumab
Research Grade Rafivirumab
Research Grade Rafivirumab
価格(USD): $
スペック:
  • 100ug
  • 1mg
数量:
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  • 概要

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  • データシート

概要
カタログ番号VK632026
説明
Rafivirumab (VK632026) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Rabies virus (RABV)
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
アイソタイプIgG1, lambda
発現システム Mammalian Cells
クローン性 Monoclonal
ターゲット G/Glycoprotein
エンドトキシンレベル Please contact the lab for this information.
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 O92284
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名CR57, NM57, S057, CR57, SO57, Ormutivimab, 944548-37-2
背景

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • Research Grade Rafivirumab

    SEC-HPLC

    SEC-HPLC detection for Research Grade Rafivirumab.

  • Research Grade Rafivirumab

    Bioactivity

    Detects Human G/Glycoprotein in indirect ELISAs.

  • Research Grade Rafivirumab

    SDS-PAGE

    SDS-PAGE for Research Grade Rafivirumab

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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