

| カタログ番号 | DY353028 |
|---|---|
| 説明 |
Dalotuzumab ELISA Kit (DY353028) — Quantitative sandwich ELISA for Dalotuzumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
|
| サンプルタイプ | Plasma, Serum |
| 感度 | 0.156 μg/ml |
| レンジ | 0.31-5 μg/mL |
| アクセッション番号 | P08069 |
| アプリケーション | ELISA |
| 検出方法 | Colorimetric |
| アッセイタイプ | Quantitative |
| 回収率 | 80-120% |
| 発送 | 2-8 ℃ |
| 安定性と保存 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 仕様 | Dalotuzumab |
| 別名 | MK-0646, 1005389-60-5 |
| 背景 | Insulin-like growth factor 1 receptor (Dalotuzumab) is a ~154 kDa protein. Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. |
| 注意事項 | For Research Use Only. |
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