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Dalotuzumab ELISA Kit (DY353028)

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概要
カタログ番号DY353028
説明
Dalotuzumab ELISA Kit (DY353028) — Quantitative sandwich ELISA for Dalotuzumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • High Sensitivity — Optimized for low-abundance target detection.
  • Ready-to-Use — Complete kit with pre-coated plates included.
サンプルタイプPlasma, Serum
感度0.156 μg/ml
レンジ0.31-5 μg/mL
アクセッション番号 P08069
アプリケーション ELISA
検出方法 Colorimetric
アッセイタイプ Quantitative
回収率 80-120%
発送 2-8 ℃
安定性と保存 The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
仕様

Dalotuzumab

別名MK-0646, 1005389-60-5
背景

Insulin-like growth factor 1 receptor (Dalotuzumab) is a ~154 kDa protein. Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins.

注意事項 For Research Use Only.
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参考文献
データシート
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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