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| カタログ番号 | DF879038 |
|---|---|
| 説明 |
Golimumab ELISA Kit (DF879038) — Quantitative sandwich ELISA for Golimumab. Sample: Plasma, Serum. Range: 62.5 - 4, 000 ng/mL. Sensitivity: 40.1 ng/mL.
Highlights
|
| サンプルタイプ | Plasma, Serum |
| 感度 | 40.1 ng/mL |
| レンジ | 62.5 - 4, 000 ng/mL |
| アクセッション番号 | CAS: 476181-74-5 |
| アプリケーション | ELISA |
| 検出方法 | Colorimetric |
| アッセイタイプ | Quantitative |
| 回収率 | 80-120% |
| 発送 | 2-8 ℃ |
| 安定性と保存 | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃. |
| 仕様 | Golimumab |
| 別名 | CNTO 148, 476181-74-5 |
| 背景 | Golimumab (Simponi®) is a human immunoglobulin G1? monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-a (TNFa). In 2009, it was approved by FDA for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis in adult patients. Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Increased levels of TNF are also found in psoriasis (Ps) plaques. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF. |
| 注意事項 | For Research Use Only. |
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