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Anti-Human CD307e/FCRL5 Antibody (SAA0316), PerCP (HV698147)

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概要

カタログ番号	HV698147
説明	Anti-Human CD307e/FCRL5 Antibody (SAA0316), PerCP [SAA0316] (HV698147) is a mouse monoclonal antibody detecting CD307e in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
種反応性	Human
アプリケーション	ELISA, FCM
宿主種	Mouse
アイソタイプ	IgG2a, kappa
クローンID	SAA0316
抱合	PerCP
クローン性	Monoclonal
ターゲット	FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, CD307
エンドトキシンレベル	Please contact with the lab for this information.
アクセッション番号	Q96RD9
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. 1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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参考文献

データシート

Anti-Human CD307e/FCRL5 Antibody (SAA0316), PerCP.pdf

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Anti-Human CD307e/FCRL5 Antibody (SAA0316), PerCP