ホーム > 製品 > 抗体 > 1次抗体

InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18) (HB852010)

データシート製品共有情報コピー

InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18)

InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18)

価格(USD): $

スペック:

100ug
1mg

数量:

お問い合わせ

概要
イメージ
参考文献
データシート

概要

カタログ番号	HB852010
説明	InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18) [K1-18] (HB852010) is a mouse monoclonal antibody detecting Thyroid-stimulating hormone receptor in Agonist, ELISA, IHC. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	Agonist, ELISA, IHC
宿主種	Mouse
アイソタイプ	IgG2a, kappa
クローンID	K1-18
クローン性	Monoclonal
ターゲット	Thyroid-stimulating hormone receptor, TSH-R, TSHR, Thyrotropin receptor, LGR3
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P16473
RRID	InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18) (abinScience Cat# HB852010, RRID:AB_3726917)
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Thyrotropin receptor (TSHR/LGR3) is a ~86 kDa protein. Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. TSHR is coupled to G(s) proteins and mediates the activation of adenylate cyclase. This leads to the generation of cyclic adenosine monophosphate (cAMP), which in turn activates protein kinase A (PKA). PKA subsequently phosphorylates downstream targets involved in thyroid hormone biosynthesis and secretion, including thyroid peroxidase (TPO) and the sodium/iodide symporter (NIS). 1. Costagliola, S. et al. (2002) The EMBO journal 21, 504-13. PMID: 11847099 2. Nakabayashi, K. et al. (2002) The Journal of clinical investigation 109, 1445-52. PMID: 12045258 3. Faust, B. et al. (2022) Nature 609, 846-853. PMID: 35940205 4. Duan, J. et al. (2022) Nature 609, 854-859. PMID: 35940204 5. Morgan, SJ. et al. (2016) Thyroid : official journal of the American Thyroid Association 26, 1794-1803. PMID: 27638195
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18)

参考文献

データシート

InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

レコメンデーション

お問い合わせカスタムクォート、大量リクエストおよびその他の問題については

メール: support@abinScience.com

ディストリビューターリスト

InVivoMAb Anti-Human TSHR/LGR3 Antibody (K1-18)