Research Grade Gantenerumab

Overview

Catalog No.

HY235036

Host species

Human

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Purity

>95% purity as determined by SDS-PAGE.

Clonality

Monoclonal

Isotype

IgG1-kappa

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Target

AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

Please contact the lab for this information.

Expression system

Mammalian Cells

Accession

P05067

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternative name

R1450, 1043556-46-2

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Gantenerumab.

SDS-PAGE

SDS-PAGE for Research Grade Gantenerumab.

Flow Cytometry

Flow-cytometry using anti-human APP antibody. SH-SY5Y cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human APP monoclonal antibody (Catalog HY235036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.